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Dernières publications
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Dylan Moutachi, Janek Hyzewicz, Pauline Roy, Mégane Lemaitre, Damien Bachasson, et al.. Treadmill running and mechanical overloading improved the strength of the plantaris muscle in the dystrophin‐desmin double knockout (DKO) mouse. The Journal of Physiology, In press, ⟨10.1113/JP286425⟩. ⟨hal-04643936⟩
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Medhi Hassani, Dylan Moutachi, Mégane Lemaitre, Alexis Boulinguiez, Denis Furling, et al.. Beneficial effects of resistance training on both mild and severe mouse dystrophic muscle function as a preclinical option for Duchenne muscular dystrophy. PLoS ONE, 2024, 19, ⟨10.1371/journal.pone.0295700⟩. ⟨hal-04501283⟩
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Antonio Atalaia, Dagmar Wandrei, Nawel Lalout, Rachel Thompson, Adrian Tassoni, et al.. EURO-NMD registry: federated FAIR infrastructure, innovative technologies and concepts of a patient-centred registry for rare neuromuscular disorders. Orphanet Journal of Rare Diseases, 2024, 19 (1), pp.66. ⟨10.1186/s13023-024-03059-3⟩. ⟨hal-04460667⟩
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Florent Porquet, Lin Weidong, Kévin Jehasse, Hélène Gazon, Maria Kondili, et al.. Specific DMPK-promoter targeting by CRISPRi reverses myotonic dystrophy type 1-associated defects in patient muscle cells. Molecular Therapy - Nucleic Acids, 2023, 32, pp.857 - 871. ⟨10.1016/j.omtn.2023.05.007⟩. ⟨hal-04287597⟩
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Caroline Le Guiner, T Larcher, A Lafoux, G Toumaniantz, S Webb, et al.. Characterization of the muscular and cardiac diseases of the DMSXL mouse model, a transgenic mouse model for Myotonic Dystrophy type 1. American Society of Gene & Cell Therapy, May 2023, LOS ANGELES, United States. ⟨hal-04096181⟩
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Dylan Moutachi, Mégane Lemaitre, Clément Delacroix, Onnik Agbulut, Denis Furling, et al.. Valproic acid reduces muscle susceptibility to contraction‐induced functional loss but increases weakness in two murine models of Duchenne muscular dystrophy. Clinical and Experimental Pharmacology and Physiology, In press, ⟨10.1111/1440-1681.13804⟩. ⟨hal-04146953⟩
Chiffres clés
144
Publications avec texte intégral
Open Access
53 %
Mots clés
Myelin
Heart
Exercice
Myotonic Dystrophy
Exercise
Myotonic dystrophy
Glucocorticoids
Transgenic mouse
RNA splicing
Alternative splicing
Gene editing
DMSXL mice
Humans
Transgenic mouse model
Glucocorticoid-receptor
Mice
PacBio
CMS
Therapy
Diaphragm
Mouse models
KNOCKOUT MICE
Myostatin
Duchenne muscular dystrophy
GABA
Cell penetrating peptide
Myotonic Dystrophy Type 1
RNA interference
Autophagy
Brain
RNA biology
AAV
Cells
Fibrosis
Motoneuron
Neuron
Transcriptomics
Dynamin 2
Brain dysfunction
CTG repeats
PCR
Male
Glial cells
Mouse model
Hypoxia
Acute coronary syndrome
Oligodendrocytes
MBNL
Centronuclear myopathy
Astrocyte
Central nervous system
Cell model
Myotonic dystrophy type 1
Myotonic dystrophy mouse models
Genotype phenotype correlation
Antisense oligonucleotide
ACETYLCHOLINESTERASE
GSK3
Muscle
Aging
Cardiac muscle
Cytoskeleton
CRISPR/Cas9
DM1
Oligodendrocyte
Trinucleotide Repeat Expansion
Dystrophie Myotonique
CTG repeat instability
DMPK
Dystrophie myotonique
Dystrophin
Myotonic Dystrophy type 1
Thérapie génique
Dilated cardiomyopathy
CONGENITAL MYATHENIC SYNDROME
Desmin
Gene Therapy
BIOLOGIE MOLECULAIRE
Cell culture model
Astrocytes
Glutamate
Acetylcholinesterase deficiency
Maximal force
Quantitative microdialysis
Muscular dystrophy
Heart failure
Trinucleotide repeat expansion
CTG repeat contractions
Expression
Long read sequencing
ARN
Cultured
Gene therapy
Acetylcholinesterase knockout mouse
Endurance training
Antisense oligonucleotides
Animals
Intermediate filament
CRISPRi
Skeletal muscle