Reconstruction of past glacier fluctuations is an important step towards the comprehension of glacier responseto past and future climate changes. Moraine deposits and roches moutonnées represent univocal geomorphicmarkers of advanced glacier extensions, and their dating using in situ-produced cosmogenic nuclides is a valuableapproach for better constraining past glacier behavior.To better understand the past glacier fluctuations in the European Alps, this study focuses on the Argentièreglacier, located on the north-western flank of the Mont-Blanc massif (MBM) in the Western Alps, and hostingsome of the largest European glaciers. Here, gemorphological analysis and new 10Be exposure ages obtained frommoraine boulders and roches moutonnées surfaces on the left-lateral side of the Argentière glacier are presented.The exposure ages of the investigated roches moutonnées suggest that the Early Holocene deglaciation in thestudied area started around 11 ka ago. The adjacent lateral moraines indicate that the glacier oscillated at leastthree times during the subsequent millennium. Afterwards, around 10 ka ago, it retreated within the Little Ice Age(LIA) limits represented by the largest moraine. The geometry and proximity of these Early Holocene and LIAmoraines suggest that the glacier had nearly the same thickness at roughly 2200 m a.s.l. during those two periods.The obtained chronology is in agreement with several other studies in the western and central parts of the Alps,implying that throughout the Alps, glacier behavior was synchronous at the beginning of the Holocene. Based onthese data and additional 10Be exposure ages obtained from Argentière glacier frontal moraines located almost 2.5km outboard of the LIA terminus, we will present potential climate scenarios for the studied periods in comparisonwith the LIA and the present. Furthermore, the influence of local factors versus regional and hemispheric climatedrivers responsible for the observed glacier fluctuations will be discussed